Combined Esophageal Intraluminal Impedance, pH and Skin Conductance Monitoring to Detect Discomfort in GERD Infants

Combined Esophageal Intraluminal Impedance, pH and Skin Conductance Monitoring to Detect Discomfort in GERD Infants

BACKGROUND The clinical significance of weakly acidic reflux in infants is unclear. Skin conductance is a novel not-invasive method to evaluate discomfort. The aim of our study was to evaluate reflux-induced discomfort in infants with gastroesophageal reflux disease using simultaneously combined skin conductance and esophageal multichannel intraluminal impedance and pH monitoring. METHODOLOGY...

Esophageal pH and Combined Impedance-pH Monitoring in Children

Esophageal pH monitoring is considered the gold standard for the diagnosis of gastroesophageal reflux disease because of the normal ranges across the pediatric age range. However, this method can only detect acid reflux. Multichannel intraluminal impedance-pH (MII-pH) monitoring has recently been used for the detection of bolus reflux in infants and children. This method allows for the detectio...

Prognostic Values of Multichannel Intraluminal Impedance and pH Monitoring in Newborns with GERD Symptoms

How to Interpret Esophageal Impedance pH Monitoring

Esophageal impedance pH monitoring provides quantitative data on esophageal acid exposure and has the ability to correlate the symptoms with acid exposure events. The nomenclature for the reflux patterns detected in impedance pH monitoring as well as the normal values have been determined. Data interpretation is similar to 24-hour pH monitoring, ie, searching for an increase in the number of re...

Effect of Gaviscon Infant on gastro-oesophageal reflux in infants assessed by combined intraluminal impedance/pH.

BACKGROUND Gaviscon Infant (GI) has been recommended for gastro-oesophageal reflux (GOR) in infants. Its efficacy has not been examined with a physiologically appropriate denominator to define the degree of GOR. AIM To investigate the influence of Gaviscon Infant on GOR in infants using combined pH and intraluminal impedance measurement. METHODS Twenty infants (mean age 163.5 days, range 34...